A Wisconsin teen with Down syndrome will have a very special prom date this weekend — a bona fide beauty queen.

In what’s believed to be a first-of-its-kind case, a family is bringing a federal lawsuit after a photo of their son with Down syndrome was doctored and spread across the Internet.

Disability advocates are calling for the Justice Department to investigate the death of a man with Down syndrome who was restrained after refusing to leave a movie theater.

Fox’s “Glee” is generating controversy after depicting a character with Down syndrome bringing a gun to school.

Despite paying for a membership, a family claims they were barred from entering a local gym because their teen daughter has Down syndrome.

A 30-year-old with Down syndrome proved so inspirational to the Cincinnati Reds during a stint as a batboy that he will soon be the subject of an ESPN profile.

Days after a grand jury determined there was no crime in the death of a 26-year-old with special needs who was restrained by law enforcement, the Justice Department is keeping a watchful eye.

A 15-year-old with Down syndrome is said to be the first American with the chromosomal disorder to make it to the base camp of the world’s tallest mountain.

In a case that drew national attention, officials say no charges will be filed in the death of a 26-year-old with Down syndrome who was restrained after refusing to leave a movie theater.

Zack Prince loves receiving snail mail. So for his birthday, Prince’s mom put out a Facebook request for cards and boy have people responded.

When she couldn’t find any dolls that looked like her daughter with Down syndrome, a Pennsylvania mom decided to create them herself.

The key to improving cognition in those with Down syndrome could be as simple as stepping onto a bike, researchers say.